Effects of High Fructose Intake on the Gut Microbiome (A Systematic Review) Yovita Puri Subardjo, Nabila Monica Khairunnissa, Mila Kartika, Fifi Yulisa Hasanah, Binta Febriana Zahra Setiawan, Ariqa Nurrahmaningsih
Department of Nutrition, Faculty of Health Sciences, Universitas Jenderal Soedirman
Abstract
The gut microbiota is a microbial ecosystem made up of a wide variety of microorganisms in the digestive system. Dysbiosis has been linked to diseases such as Inflammatory Bowel Disease (IBD), obesity, type 1 and 2 diabetes mellitus, autism and certain gastrointestinal cancers. Fructose is commonly referred to as fruit sugar and is the sweetest sugar currently found in packaged beverages. High fructose intake is known to cause changes in the gut microbiota. This literature review aims to evaluate the impact of high fructose consumption on gut microbiota balance. The data used came from articles sourced from electronic databases such as Google Scholar, Science Direct, and PubMed published within 10 years, from 2013 to 2022, and in English. The keywords used were ^high fructose intake^ AND ^gut microbiome^ OR ^gut microbiota^. From these criteria, 88 journals were obtained and after several selections, nine journals were obtained and will be reviewed. Based on the nine articles reviewed, it was found that a high-fructose diet affected the gut microbiota. High fructose intake at doses between 10-60% is known to decrease or increase the number of microbiota in the gut. Thus, it can be concluded that high fructose intake can affect the balance of the gut microbiome.
Keywords: high fructose intake- gut microbiome- gut microbiota
