Effect of Ethanol Extract of Lemongrass Plant (Cymbopogon Citratus), Ginger (Zingiber Officinale Rosc.), Pandan Leaf (Pandanus Amaryllifolius), And Cinnamon (Cinnamomum Burmanii) On Albumin And Blood Globulin Levels In Wistar Rats (Rattus Norvegicus) given high fat Ida Duma Riris, Marini Damanik, Tita juwitaningsih, Romondang Fransiska Tampubolon and Ely Sabet Pratiwi Siagian
FMIPA UNIMED
Abstract
This study aimed to determine the administration of a mixture of lemongrass ethanol extract (Cymbopogon citratus), ginger (Zingiber officinale Rosc.), pandan leaves (Pandanus amaryllifolius), and cinnamon (Cinnamomum burmanii) against high fat-induced blood albumin and globulin levels of wistar rats. The method was carried out by dividing the mice with 7 treatment groups and 4 tests, including KO + (Groups given standard feed)- KO- (Controls fed with high-fat standard an feed)- K+ (Simvastatin-given controls),K1, K2, K3and K4 at a dosage of 100,200,300,and400 mg/Kg BB plant extract mixture of ginger, lemongrass, cinnamon and pandan leaves). The data was analyzed with SPSS software for windows. The results showed that giving a mixture of ethanol extracts of lemongrass plants, ginger, pandan leaves, and cinnamon affected the blood albumin and globulin levels of wistar rats. A significant increase was shown in K4 (400mg/Kg BB) with normal rat levels, namely for albumin 4.8 g/dL and globulins of 3.9 g/dL. With shapiro Wilk Normality Test analysis with sig 0.05, normal distributed data. The Test of Homogeneity of Variances obtained a calculated f value greater than the f table which showed that plant extracts have the potential to increase and stabilize albumin and globulin levels.
Keywords: Albumin and Globulin- ethanol extract- mixing of : lemongrass, ginger, pandan leaves, and cinnamon
