Changes in Components of Metabolic Syndrome on Health-Related Quality of Life in Adults in Bogor City
Titi Indriyati1, Asri C. Adisasmita2, Mardiati Nadjib2, Ratna Djuwita Hatma2, Imam Subekti3, Soewarta Kosen4, Woro Riyadina5, Telly Purnamasari5

1Fakultas Kesehatan Universitas Mohammad Husni Thamrin
2Fakultas Kesehatan Masyarakat Universitas Indonesia
3Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo
4Kementerian Kesehatan Republik Indonesia
5Badan Riset dan Inovasi Nasional (BRIN)

Abstract

Background: Metabolic syndrome (MS) is a chronic clinical condition, where each component can change and affect quality of life.
Purpose: This study aims to assess changes in the components of metabolic syndrome on health-related quality of life.
Methods: The study approach uses a follow-up prevalence design as a cross-sectional derivative of the main cohort study. The diagnosis of MS was the number of criteria for MS is more than 3 out of 5 components using data from a cohort study of NCD risk factors by the Research and Development Center of the Ministry of Health of the Republic of Indonesia in Central Bogor District. Changes in MS components are seen in three monitoring times. Period 1 in 2011/2012, period 2 in 2013/2014, and period 3 in 2017/2018. The HRQoL interview was conducted in 2021 with 874 respondents using the EQ-5D-5L questionnaire.
Results: The components of MS in the third monitoring period were: central obesity in men 23.2%- women 78.6%- low HDL levels in men 31%- women 36.4%- hypertension 35.5%- high triglycerides >150 mg/dl 21.9%- fasting blood sugar >100 mg/dl is 38.2%. The component of MS associated with low quality of life below the mean EQ-VAS for Indonesians is central obesity in women, POR (95% CI) = 2.3 (0.9 - 5.4), FBS level <100 mg/dl with a POR (95% CI) = 1.8 (1.1-2.9). HRQoL in a low health profile is in the dimensions of limited mobility, self-care, daily activities, and discomfort/pain, and these problems are most affected by central obesity, hypertension, and FBS levels >100 mg /dl. Whereas on the dimensions of anxiety or depression, it was only affected by hypertension (POR = 1.8 [1.1-2.9]).
Conclusion: Hypertension is most associated with low HRQoL in the EQ-5D health profile. Developing more proactive health and Germas intervention programs in the community is necessary.

Keywords: changes, components, metabolic syndrome, health-related quality of life, EQ-5D

Topic: Communicable and non communicable disease